integrity - Assessing the Integrity and Trustworthiness of Clinical Trials
Data
The integrity package implements the IPD Integrity Tool, a
structured and transparent framework for evaluating the
integrity of individual participant data (IPD) from randomised
trials (see Hunter et al. (2024) <doi:10.1002/jrsm.1738> and
<doi:10.1002/jrsm.1739>). It supports users to identify
potential issues, such as unusual data patterns, implausible
values, lack of expected correlations, date violations, and
inconsistencies. The package provides reproducible workflows
for screening, documenting and summarising integrity concerns,
and may be applied by evidence synthesists, editors, and others
to determine whether a randomised trial may be considered
sufficiently trustworthy to contribute to the evidence base
that informs policy and practice.
